Research at VVP focuses on basic and applied science in three main areas:  vascular disease, oncology, and opthamological disorders. Concepts that are applied within these three focus areas include angiogenesis modulation, including novel therapeutic and diagnostic targets; chemoresistance and methods to enhance chemotherapeutic uptake; the role of platelets and platelet activation in tumor metastasis; prevention and treatment of tumor-related thrombosis; and novel approaches to the treatment and prevention of ischemia and coronary artery diseases.